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Drug-Processing Gene Test

Connecticut rates for HCPCS 81231

Reads a gene that controls one of the liver enzymes the body uses to break down medicines. People carry different versions, and some clear certain drugs much faster or slower than average, which is why an ordinary dose can be ineffective for one person and too strong for another.

Rates data updated October 2026.

How much does Drug-Processing Gene Test cost?

$162

Typical negotiated rate. In Connecticut, October 2026.

Insurers have agreed to pay about $162 for this service. Most negotiated rates run $105 to $229.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $219 · 10th to 90th $132 to $437Professionalmedian $115 · 10th to 90th $89 to $263
$100$200$500facility $219professional $115

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
None
Typical Low
$95.50
Median
$114.82
Typical High
$123.03
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$131.83
Median
$218.78
Typical High
$436.52
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$79.43
Median
$104.71
Typical High
$223.87
Cigna
Setting
Facility
Modifier
None
Typical Low
$173.78
Median
$275.42
Typical High
$630.96
Cigna
Setting
Professional
Modifier
None
Typical Low
$95.50
Median
$194.98
Typical High
$354.81
ConnectiCare
Setting
Professional
Modifier
None
Typical Low
$173.78
Median
$234.42
Typical High
$281.84
United
Setting
Professional
Modifier
None
Typical Low
$74.13
Median
$104.71
Typical High
$223.87
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$47.86
Median
$57.54
Typical High
$61.66
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$19.05
Median
$22.91
Typical High
$24.55

Where Connecticut sits

The same service costs 3.7 times more in Alaska than in Oklahoma. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Connecticut· 32nd of 51

$162

AK $389OK $105

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.