High-Risk Hpv Active Infection Rna Test

Illinois rates for HCPCS 0354U

Detects infection with seven high-risk types of human papillomavirus (HPV 16, 18, 31, 33, 45, 52 and 58), the strains most associated with cervical and other cancers. Rather than looking for viral DNA, it looks for the E6 and E7 messenger RNA the virus makes when it is actively driving cell changes, and reports whether each is found.

Rates data updated October 2026.

How much rates vary

Facilitymedian $98 · 10th to 90th $56 to $186Professionalmedian $45 · 10th to 90th $45 to $56

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier	Facility/Professional	Modifier	Typical Low	Median	Typical High
BCBS Illinois Setting Facility Modifier None Typical Low $56.23 Median $97.72 Typical High $186.21	Facility	None	$56.23	$97.72	$186.21
Cigna Setting Professional Modifier None Typical Low $44.67 Median $44.67 Typical High $56.23	Professional	None	$44.67	$44.67	$56.23