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Blood Tumor DNA Panel With MSI And TMB

Minnesota rates for HCPCS 0326U

Guides treatment choice in solid tumors from a blood sample rather than tumor tissue. Fragments of tumor DNA circulating in the blood are sequenced across at least eighty-three genes, and microsatellite instability and tumor mutational burden are reported as well — two measures counted beyond that gene total.

Rates data updated October 2026.

How much does Blood Tumor DNA Panel With MSI And TMB cost?

$5,012

Typical negotiated rate. In Minnesota, October 2026.

Insurers have agreed to pay about $5,012 for this service. The price depends on where it is billed: about $5,012 from a physician practice, and about $5,012 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$5,012$4,365 to $6,026
FacilityA hospital or hospital-owned outpatient department$5,012$4,677 to $12,882

How much rates vary

Facilitymedian $5,012 · 10th to 90th $4,677 to $19,498Professionalmedian $5,012 · 10th to 90th $3,020 to $9,772
$2K$5K$10K$20K$50Kfacility $5,012professional $5,012

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$4,677.35
Median
$4,677.35
Typical High
$4,677.35
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$4,677.35
Median
$4,677.35
Typical High
$4,786.30
BCBS Minnesota
Setting
Facility
Modifier
None
Typical Low
$4,466.84
Median
$5,011.87
Typical High
$5,011.87
BCBS Minnesota
Setting
Professional
Modifier
None (both parts)
Typical Low
$3,981.07
Median
$4,466.84
Typical High
$5,011.87
Cigna
Setting
Facility
Modifier
None
Typical Low
$10,232.93
Median
$15,848.93
Typical High
$46,773.51
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$5,754.40
Median
$6,606.93
Typical High
$9,772.37
Health Partners
Setting
Facility
Modifier
None
Typical Low
$9,332.54
Median
$15,488.17
Typical High
$37,153.52
Health Partners
Setting
Professional
Modifier
None (both parts)
Typical Low
$5,754.40
Median
$5,754.40
Typical High
$8,912.51
Medica
Setting
Facility
Modifier
None
Typical Low
$7,244.36
Median
$8,128.31
Typical High
$10,000.00
Medica
Setting
Professional
Modifier
None (both parts)
Typical Low
$2,570.40
Median
$5,623.41
Typical High
$25,118.86
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$2,089.30
Median
$3,981.07
Typical High
$11,748.98
6 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Facility
Modifier
26 · Professional part
Typical Low
$4,677.35
Median
$4,677.35
Typical High
$4,677.35
Aetna
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$2,344.23
Median
$2,344.23
Typical High
$2,344.23
Aetna
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$933.25
Median
$933.25
Typical High
$933.25
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$4,677.35
Median
$4,677.35
Typical High
$4,677.35
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$2,344.23
Median
$2,344.23
Typical High
$3,019.95
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$933.25
Median
$933.25
Typical High
$1,202.26

Where Minnesota sits

The same service costs 12.0 times more in Texas than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Minnesota· 14th of 51

$5,012

TX $25,119AL $2,089

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.