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BCR-ABL1 Major Breakpoint Measurement

North Carolina rates for HCPCS 0040U

Used in chronic myeloid leukemia to measure how much of the abnormal BCR-ABL1 gene fusion is present, which shows how the disease is responding. It reports a quantity for the major breakpoint form of the fusion only; a companion test covers both breakpoint forms.

Rates data updated October 2026.

How much does BCR-ABL1 Major Breakpoint Measurement cost?

$457

Typical negotiated rate. In North Carolina, October 2026.

Insurers have agreed to pay about $457 for this service. The price depends on where it is billed: about $457 from a physician practice, and about $891 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$457$372 to $759
FacilityA hospital or hospital-owned outpatient department$891$646 to $1,862

How much rates vary

Facilitymedian $891 · 10th to 90th $331 to $1,862Professionalmedian $457 · 10th to 90th $245 to $1,202
$200$500$1K$2Kfacility $891professional $457

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$758.58
Median
$758.58
Typical High
$758.58
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$302.00
Median
$489.78
Typical High
$758.58
BCBS
Setting
Professional
Modifier
None (both parts)
Typical Low
$371.54
Median
$467.74
Typical High
$1,445.44
Cigna
Setting
Facility
Modifier
None
Typical Low
$338.84
Median
$1,071.52
Typical High
$1,862.09
Medcost
Setting
Facility
Modifier
None
Typical Low
$331.13
Median
$331.13
Typical High
$489.78
Medcost
Setting
Professional
Modifier
None (both parts)
Typical Low
$457.09
Median
$457.09
Typical High
$707.95
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$173.78
Median
$245.47
Typical High
$457.09
9 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$331.13
Median
$331.13
Typical High
$380.19
Medcost
Setting
Professional
Modifier
26 · Professional part
Typical Low
$181.97
Median
$181.97
Typical High
$302.00
Medcost
Setting
Professional
Modifier
50 · Both sides
Typical Low
$676.08
Median
$676.08
Typical High
$1,698.24
Medcost
Setting
Professional
Modifier
51 · Multiple procedures
Typical Low
$229.09
Median
$229.09
Typical High
$562.34
Medcost
Setting
Professional
Modifier
80 · Assistant surgeon
Typical Low
$91.20
Median
$91.20
Typical High
$223.87
Medcost
Setting
Professional
Modifier
81 · Minimal assistant surgeon
Typical Low
$63.10
Median
$63.10
Typical High
$158.49
Medcost
Setting
Professional
Modifier
82 · Assistant surgeon, no resident
Typical Low
$63.10
Median
$63.10
Typical High
$158.49
Medcost
Setting
Professional
Modifier
AS · PA/NP assist
Typical Low
$63.10
Median
$63.10
Typical High
$158.49
Medcost
Setting
Professional
Modifier
TC · Technical part
Typical Low
$426.58
Median
$426.58
Typical High
$707.95

Where North Carolina sits

The same service costs 11.7 times more in Texas than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

North Carolina· 14th of 51

$457

TX $2,042AL $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.