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BCR-ABL1 Major Breakpoint Measurement

Missouri rates for HCPCS 0040U

Used in chronic myeloid leukemia to measure how much of the abnormal BCR-ABL1 gene fusion is present, which shows how the disease is responding. It reports a quantity for the major breakpoint form of the fusion only; a companion test covers both breakpoint forms.

Rates data updated July 2026.

How much does BCR-ABL1 Major Breakpoint Measurement cost?

$457

Typical negotiated rate. In Missouri, July 2026.

Insurers have agreed to pay about $457 for this service. The price depends on where it is billed: about $309 from a physician practice, and about $646 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$309$204 to $550
FacilityA hospital or hospital-owned outpatient department$646$407 to $724

How much rates vary

Facilitymedian $646 · 10th to 90th $407 to $955Professionalmedian $309 · 10th to 90th $81 to $724
$100$200$500$1K$2Kfacility $646professional $309

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$537.03
Median
$707.95
Typical High
$954.99
Aetna
Setting
Professional
Modifier
Global
Typical Low
$398.11
Median
$691.83
Typical High
$1,412.54
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$407.38
Median
$407.38
Typical High
$1,445.44
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$81.28
Median
$275.42
Typical High
$676.08
Cigna
Setting
Facility
Modifier
Global
Typical Low
$467.74
Median
$776.25
Typical High
$1,122.02
Medica
Setting
Facility
Modifier
Global
Typical Low
$354.81
Median
$489.78
Typical High
$1,949.84
Medica
Setting
Professional
Modifier
Global
Typical Low
$173.78
Median
$275.42
Typical High
$2,041.74
United
Setting
Facility
Modifier
Global
Typical Low
$190.55
Median
$407.38
Typical High
$489.78
United
Setting
Professional
Modifier
Global
Typical Low
$173.78
Median
$245.47
Typical High
$512.86

Where Missouri sits

The same service costs 11.2 times more in Alaska than in Kentucky. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 18th of 51

$457

AK $912KY $81.28

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.